Federal prosecutors have charged two former employees of Nationwide Childrenโ€™s Hospital in Ohio with stealing trade secrets for the Chinese biotech company they founded in 2015, authorities said in an indictment unsealed Monday, STAT reported

Why it matters: Trade secret theft has been a recurring theme in escalating trade tensions between the US and China. The National Institutes of Health (NIH) has been working with federal investigators to probe grant recipientsโ€™ foreign ties, particularly with China.

  • Nationwide Childrenโ€™s Hospital is one of the top-funded research institutions in the US.

โ€œNationwide Childrenโ€™s Hospital devoted years of work and its own money to researching exosomes in order to promote honorable medical advances.โ€

โ€”Benjamin Glassman, the US attorney in Ohioโ€™s Southern District

Details: Yu Zhou, 49, and his wife, Li Chen, 46, worked in separate research labs at Nationwide Childrenโ€™s Hospital in Columbus, Ohio until around two years ago. Together they founded biotech companies in both China and the US that marketed a technology called exosome isolation, which prosecutors say is based on a Nationwide Childrenโ€™s trade secret. The couple was arrested in July.

  • Exosomes are small bubble-like groups of molecules that transport proteins and genetic information between cells.
  • Effectively isolating them could open doors to more effective drug delivery techniques. 
  • According to prosecutors, Zhou and Chen received nearly $1.5 million upon co-founding their US-based company. 

Briefing: MIT scientists decry crackdown on researchers of Chinese origin

Context: While the controversial US government crackdown on intellectual property theft and misappropriation of research grant funds is sometimes lumped together as a singular effort, the consequences differ. 

  • Researchers charged with misusing NIH grant funds or failing to disclose the extent of their foreign ties were fired from their posts at research institutions or universities
  • Those accused with intellectual property theft have faced more serious consequences, with the government going as far as to request the extradition of a scientist from Switzerland on charges that also included corporate espionage. 

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